Tissue engineering and applied cell sciences

The  man-made  creation  of  tissues,  organs,  or  even  larger  organisms  was  for  a long time a matter of myth and dream throughout the history of medicine. It now comes into clinical reality. Tissue engineering and regenerative medicine are the terms that are nowadays used to describe the approach to generate complex tissues and organs from simpler pieces.  Both  are  multidisciplinary,  young  and  emerging fields in biotechnology and medicine, which are expected to change patient treatment  profoundly,  generating  and  regenerating  tissues  and  organs  instead  of  just repairing them.

Having a therapeutic application, where the tissue is either grown in a patient or outside the patient and transplanted, tissue engineering can have diagnostic applications where the tissue is made in vitro and used for testing drug metabolism and uptake, toxicity, and pathogenicity. The foundation of tissue engineering/regenerative medicine for either therapeutic or diagnostic applications is the ability to exploit living cells in a variety of ways. Tissue engineering is a more technical concept of tissue and organ reconstruction by the use of cells, scaffolds, and biomolecules.

 Applied Cell Sciences is known as a branch of biological science which is involved in isolation, derivation and, culture, manipulation and differentiation of cells towards using in treatment of various diseases.

The School of Advanced Medical Sciences and Technologies was established in 2010 as a part of Shiraz University of Medical Sciences. The education and research activities of this school are taking place in 6 departments. In the department of Tissue Engineering and Applied Cell Sciences, we
are offering two main programs in PhD degree including “Tissue Engineering” and “Applied Cell Sciences”. 

Research areas

- Design and implementation of projects in regenerative medicine, stem cell and tissue engineering technology

·         Targeted drug delivery using systems based on nanotechnology and tissue engineering

·         Gene delivery using non-viral vectors, and polymeric nanoparticles

·         Laboratory studies to investigate the toxicity of nanoparticles and bio-materials used in engineered tissue as well as for cell therapy and drug delivery

·         Design and synthesis of various scaffolds for different

·         Fabrication of biosensors by using lab on a chip system for detection and studying the functionality of tumor and cancerous cells

·         The micro/nanofluidics process for tissue engineering, cell and gene therapy

·         In situ cell therapy in a variety of end-stage and cancerous disease

·         Tissue engineering: cardiovascular, liver, gonads, eyes, nervous system, teeth, bones and cartilage ...

·         Isolation, assessment and standard banking of stem cells

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